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---Constituents---The strongest alkaloids in A. scholaris bark are Ditamine, Echitanine, the latter in character resembling ammonia other constituents are echierin, echicaoutin echitin, and echitein - these are crystalline and Echiretin amorphous. Constituents of A. constricta bark, alstonine and porphyrine, is colourless and amorphous; also contains porphyrosine and alstonidine. ---Medicinal Action and Uses---Though Alstonia is used in India and Eastern Colonies for malarial conditions, its efficacy in this respect is not to be compared with cinchona bark, though it does not produce the bad effects cinchona does. It is also employed as a bitter tonic, vermifuge, and as a cure for chronic diarrhoea and bowel complaints, both varieties are used. ---Preparation---Dita bark: 1 part in 20 for B.P. infusion, 1/2 to 1 fluid ounce; 1 part in 8 Alcohol Tinc., B.P., 1/2 to 1 fluid drachm. Dose, 2 to 4 grains. ---Other Species---The A. spectabilis, a habitat of Java, contains the same alkaloid as Dita bark, with the addition of a crystalline alkaloid, Alstonamine. [Top] © Copyright Protected 1995-2013 Botanical.com |